SR9009

SR-9009 is an advanced agent affecting the activity of nuclear receptors, responsible for the circadian rhythm as well as numerous metabolic processes. It can significantly enhance endurance and help to burn adipose tissue. Just as importantly, the compound improves lipid management, has potent anti-inflammatory properties, and is able to normalise blood glucose levels.

SR-9009, also known as Stenabolic, is a popular name of an agent whose full name is ethyl-3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate, which has been known since 2004 as an agonist of nuclear receptors REV-ERB, responsible for regulating the circadian rhythm in mammals, including humans. The receptors are located in the brain, the liver, and the most important place from the perspective of athletes: the skeletal muscles.

It has been discovered that the activation of those receptors not only stimulates the body, but also induces changes in the whole organism that resemble those caused by physical activity. In tests on animals, the agent helped to reduce adipose tissue levels in the body, and decrease lipid profile parameters, triglyceride and glucose levels. At the same time, it dramatically increased muscle endurance as well as caused positive changes in muscle tissue. Because of that, SR-9009 is sometimes referred to as “exercise in a bottle”; however, its use can be highly beneficial for individuals who stay active every day as well as those who are not fans of exercise.

Significant endurance boost

The agent has been proven to increase the number of mitochondria in muscle tissue, both by promoting the formation of new structures and limiting the breakdown of already existing organelles. As the power plant of the cell, the mitochondria are responsible for such processes as the breakdown of glucose and fats to adenosine-5’-triphosphate (ATP). Tests have also shown much higher fat and glucose uptake by muscle tissue during exercise and rest. Thanks to that, the muscles are able to produce more power, work longer, and regenerate faster between trainings.

More effective cutting with SR-9009

Thanks to the afore-mentioned increased energy substrate uptake by tissues, SR-9009 can facilitate the process of weight loss in a direct way, even without considerable changes in physical activity or the diet. According to research, the agent speeds up fat burning by even 60%. It is also worth mentioning that the stimulant properties of the substance can also contribute to higher energy expenditure during the day or during workout.

In the case of athletes, another important effect of SR-9009 is its high anti-inflammatory potential, as during the cutting stage, athletes are particularly susceptible to slower regeneration and, as a result, increased inflammatory processes. Frequently, that prevents them from keeping up with their workout plan or forces to use highly invasive, non-steroidal anti-inflammatory drugs (NSAIDs).

SR-9009 supports the development of lean muscle mass

The REV-ERB group consists of alpha and beta receptors, and SR-9009 displays closer affinity to alpha receptors. This detail is relevant because alpha receptors are dominant in terms of stimulating the growth of muscle mass, particularly the development caused by highly intensive physical effort, such as heavy strength workout. That is connected with promoting protein synthesis in fast-twitch muscle fibres, which constitute the majority of muscle tissue in strength athletes.

Moreover, the substance inhibits the expression of genes responsible for fat deposition, and its ability to maintain high insulin sensitivity enables even faster muscle growth. According to research, Stenabolic inhibits the deposition of adipose tissue during a hypercaloric diet. What is more, it reduced weight gain in mice with a modified genetic code making them more prone to severe obesity. That may suggest that thanks to SR-9009, even individuals who consider themselves to be endomorphs, that is people with a tendency to maintain higher fat levels, are able to build lean muscle mass.

It is also worth mentioning that a high aerobic capacity provided by Stenabolic helps to reduce breaks between series, which allows to increase overall workout intensity and constitutes a powerful stimulus for muscles to grow.

Better mood and circadian rhythm support

In connection with the basic role of REV-ERB receptors, their activators, like SR-9009, are able to help individuals suffering from sleep disorders. Thanks to that, Stenabolic can prove helpful in travelling between time zones (jet-lag) and working shifts. It has been observed that taking the substance can help to stay awake and keep energy levels high even 12 hours after consumption.

Moreover, SR-9009 also has a beneficial effect on the mood. It is not entirely clear if the effect stems directly from the activity of REV-ERB receptors, or the indirect effects described above. It is quite clear, however, that most users of this agent experience a visible increase in motivation and report reduced anxiety. The effect was also confirmed in tests on animal models, where the efficiency of SR-9009 proved to be comparable to that of benzodiazepine drugs.

To sum up, SR-9009 is a unique product considered to be a physical exercise mimetic. It has health-improving properties regarding the most important metabolic markers. Moreover, it can significantly affect exercise parameters, at the same time accelerating fat burning, and exerting a positive effect on the user’s mental condition.

How to use and combine SR-9009?

SR-9009 is considered particularly useful during the cutting stage, but it can, in fact, be used at any time, regardless of the stage the user is in or their physical shape. It can also help overweight people whose condition prevents them from exercising.

Because of its stimulant properties, the substance should not be taken in the afternoon or in the evening, as it can cause problems with falling asleep.

It is worth noting that using this product brilliantly aids doping products, as the mechanisms of its activity do not overlap with the pathways stimulated by SARMs, SAAs, or PPAR agonists. Moreover, the health-enhancing properties of this agent enable more efficient preventive healthcare during steroid cycles, when some disorders may occur, such as imbalanced lipid management, bile overproduction, and fat deposition in the liver.

Importantly, in tests on animals, the agent reduced cardiac hypertrophy. This fact is crucial because the majority of people who do sports for long periods of time experience increased heart mass.